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Next-generation diabetes management Glyntis™ 

An intelligent self-regulating drug delivery system.

A device-free, glucose-responsive drug delivery platform that automatically regulates insulin release using microneedles or injectable nanoparticles, simplifying diabetes care across human and veterinary markets.

Overview

Diabetes remains one of the most challenging chronic conditions globally, affecting millions of people and animals alike. Despite advances like insulin pumps and continuous glucose monitors, nearly 50% of patients do not achieve target glucose control, leading to complications and increased healthcare costs.

Our next-generation, self-regulating, glucose-responsive drug delivery platform offers a device-free, pain-free solution that closely mimics the body’s natural insulin regulation. Available in two formats — a microneedle patch and injectable glucose-sensitive nanoparticles — the platform automatically releases insulin when glucose levels rise and slows release as glucose normalises, reducing hypoglycaemia risk and treatment burden.

How It Works

Our platform integrates glucose sensing and therapeutic release in a single system.

 

It's available in two forms:

Microneedle Patch

Pain-free, dissolvable, and disposable. Designed for daily use, it provides seamless glucose-responsive insulin delivery.

Injectable Nanoparticles

Biodegradable drug storage depot that responds to glucose levels in real time, enabling targeted therapy without active patient intervention.

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Key Benefits

Device-free and stress-free

Removes the need for pumps, reduces reliance on CGMs,  manual dose adjustments and most importantly the needle pain.

Reduces hypoglycaemia risk

Insulin release automatically adjusts in response to glucose fluctuations.

Improves adherence and quality of life

Patients and animal owners no longer manage complex routines.

Cost-effective & scalable

Low production costs enable broad access, including low- and middle-income countries.

Translational potential

Applicable to both human and veterinary diabetes care, addressing global need.

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Applications & Market Potential

Our technology is designed for diverse settings: hospitals, primary care, home-based care, and veterinary clinics. It also has potential for other anti-diabetics such as GLP-1 analogues etc, and other glucose-sensitive therapies, broadening the platform’s utility.

Globally, with over 81% of people with diabetes living in low- and middle-income countries, the platform’s scalable, affordable design can transform diabetes care worldwide. In veterinary markets, it addresses a growing need for stress-free, easy-to-administer glucose management in pets and the horse racing/breeding sector.

We are actively exploring potential applications and collaborations of this technology within wound care, fermentation and bioreactor industry and food packaging sectors.

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Our Team

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Dr. Amr Elshaer

Principal Scientific Advisor

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Neeta Barot

Tech. Transfer Officer

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Nicholas Jones

Business Advisor

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Caroline Soliman

Microneedle Lead

We are seeking collaborators, investors, and partners to help bring this transformative platform to humans and animals worldwide.

If you are interested in learning more or exploring collaboration opportunities, please book a meeting via the link below:

You can also connect with Maria via LinkedIn

LinkedIn

If you can spare 2 minutes, please complete the short survey below.

Which sector best describes you?
Do you have influence over technology adoption, product development, or purchasing decisions in your organisation?
How significant are the problems caused by current insulin administration and/or glucose monitoring approaches in your sector?
What minimum cost reduction (%) would be required for your organisation to seriously consider switching to a new insulin or glucose-responsive delivery approach?
How open would your organisation be to evaluating a passive, non-electronic, glucose-responsive delivery or sensing technology if it reduced complexity and cost?
How valuable would automatic, glucose-responsive release of insulin or diabetes medication be in your context?
Which of the following would be the biggest barrier to adoption in your organisation?
If this technology could address your key pain points, how likely would your organisation be to engage in early collaboration, pilot studies, or co-development?
Would you be open to follow-up or conversation to discuss potential collaboration?
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