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RTmet by Mean Analytics

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See deeper into your bioprocess.

Mean Analytics is developing RTmet, a real-time metabolomics system for bioprocess monitoring and control. It tracks hundreds of compounds as your process runs, so you can catch drift early, reduce batch failure and improve product quality.

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What RTmet does

Mean Analytics is developing RTmet, a real-time metabolomics system for bioprocess monitoring and control.

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It combines online sampling and feeding with mass spectrometry and data analysis. That lets biomanufacturers track nutrient depletion, metabolite accumulation, toxin build-up and overall process health as it happens.

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RTmet captures ten times more chemical features than competing approaches, giving precise, label-free monitoring of hundreds of compounds, with data linked directly to titre, feedstock concentrations and key intermediates.

The problems it targets

Product variation

Low-resolution monitoring lets quality drift. RTmet helps keep products stable.

Poor productivity

It's often caused by not seeing nutrient levels clearly enough during the process.

Batch failure

Spot problems at the earliest possible stage, and save the time and cost of a lost batch.

Slow scale-up

Better process data means faster process development

Why RTmet is different

RTmet enables real-time, continuous and detailed monitor, providing valuable and actionable insights during process development, scale-up and process control. 

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Conventional process monitoring: continuous, but limited in what it measures.

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Conventional measured data: lack the sensitivity and/or coverage to show what the biology is actually doing.

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Conventional metabolomics: rich detail, but offline and retrospective – You only find out after the fact!

We're seeking partners.

RTmet is a working prototype, proven in lab and process development settings. Next, we're testing it in an industrial environment. We want to hear from fermentation-based industries, bio equipment manufacturers, pilot plants, researchers and investors.

The team behind Mean Analytics

Yuandi Zhao

Yuandi Zhao

Entrepreneurial lead and PDRA

Karl Burgess

Karl Burgess

Principal Scientific Advisor and Personal Chair of Biological Mass Spectrometry

Amy Tayler

Amy Tayler

Enterprise Executive

Eve Bird

Eve Bird

Business Advisor and R&I Consultant

Start a conversation

Whether you run, build or invest in bioprocesses, tell us what you're working on. We'd value your feedback as much as your interest.

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